Plasma Amino Acids in Experimental Acute Hepatic Failure and Their Relationship to Brain Tryptophan-Reference-Cited by-同舟云学术

Plasma Amino Acids in Experimental Acute Hepatic Failure and Their Relationship to Brain Tryptophan

Published:1974-04-01 Issue:4 Volume:46 Page:559-562
ISSN:0301-0538
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Buxton B. H.¹,Stewart D. A.¹,Murray-Lyon I. M.¹,Curzon G.¹,Williams R.¹

Affiliation:

1. Liver Unit, Kings College Hospital, London, and Department of Neurochemistry, Institute of Neurology, London

Abstract

1. Sixteen plasma amino acids were measured serially in an experimental model of acute hepatic failure produced in the pig by devascularization of the liver. 2. Significant increases in the concentration of glycine, alanine and methionine were observed. 3. Altered concentrations in plasma of neutral amino acids which compete with tryptophan for transport into the brain had no apparent influence on brain tryptophan concentration.

Publisher

Portland Press Ltd.

Subject

General Medicine

Link

http://portlandpress.com/clinsci/article-pdf/46/4/559/815383/cs0460559.pdf

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