Author:
Andersson B,Jones D P,Orrenius S
Abstract
The effect of extracellular Ca2+ concentration on ethanol oxidation and drug metabolism was studied in isolated rat hepatocytes. Both ethanol oxidation and drug glucuronidation showed similar dependence upon Ca2+, which was a stimulation of activity as Ca2+ was increased to physiological concentration, and inhibition at higher concentration.
Subject
Cell Biology,Molecular Biology,Biochemistry
Cited by
9 articles.
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