Lens and retina regeneration: new perspectives from model organisms

Author:

Barbosa-Sabanero Karla1,Hoffmann Andrea2,Judge Chelsey1,Lightcap Nicole1,Tsonis Panagiotis A.2,Del Rio-Tsonis Katia1

Affiliation:

1. Department of Zoology, Miami University, Oxford, OH 45056, U.S.A.

2. Department of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, OH 45469-2320, U.S.A.

Abstract

Comparative studies of lens and retina regeneration have been conducted within a wide variety of animals over the last 100 years. Although amphibians, fish, birds and mammals have all been noted to possess lens- or retina-regenerative properties at specific developmental stages, lens or retina regeneration in adult animals is limited to lower vertebrates. The present review covers the newest perspectives on lens and retina regeneration from these different model organisms with a focus on future trends in regeneration research.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry

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