A Circulating Humoral Pressor Agent in Dahl S Rats with Salt Hypertension-Reference-Cited by-同舟云学术

A Circulating Humoral Pressor Agent in Dahl S Rats with Salt Hypertension

Published:1979-12-01 Issue:s5 Volume:57 Page:345s-347s
ISSN:0144-9664
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Tobian L.¹,Pumper Mary¹,Johnson Susan¹,Iwai J.¹

Affiliation:

1. Hypertension Section, University of Minnesota Hospital and School of Medicine, Minneapolis, Minnesota and Brookhaven National Laboratory, Upton, New York, U.S.A.

Abstract

1. In Dahl S rats becoming hypertensive while on a diet of high NaCl content there appears to be a blood-borne humoral agent which produces vasoconstriction in a bioassay using the isolated hindquarters of rats. 2. This vasoconstrictor effect strongly suggests the presence of a humoral pressor agent or the lack of a vasodilator agent in the blood of hypertensive S rats. 3. The vasoconstrictor effect is not due to high renin concentrations. 4. This humoral vasoconstrictor action could partly account for the high vascular resistance in the hypertensive S rat.

Publisher

Portland Press Ltd.

Subject

Ocean Engineering

Link

https://portlandpress.com/clinsci/article-pdf/57/s5/345s/875934/cs057345s.pdf

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