Affiliation:
1. Department of Rheumatology, University Hospital, Zurich, Switzerland.
Abstract
Equations are described for the analysis of enzyme-catalysed reactions in the presence of hyperbolic tight-binding inhibitors using both graphical and non-linear-regression methods. The general character of the equations allows the interpretation of several other kinetic mechanisms. As an example, the tight-binding hyperbolic non-competitive inhibition of human leucocyte elastase by a polysulphated glycosaminoglycan is analysed.
Subject
Cell Biology,Molecular Biology,Biochemistry
Cited by
18 articles.
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