1. Clinical Pharmacology Unit, Addenbrooke's Centre for Clinical Investigation, Box 110, Addenbrooke's Hospital, University of Cambridge, Cambridge, U.K.
2. Department of Clinical Pharmacology, St Thomas' Hospital, London, U.K.
3. Chiltern International Ltd, Chiltern House, Stoke Poges, U.K.
4. Protherics plc, Runcorn, U.K.