The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function-Reference-Cited by-同舟云学术

The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function

Published:2015-04-17 Issue:3 Volume:467 Page:473-486
ISSN:0264-6021
Container-title:Biochemical Journal
language:en
Short-container-title:

Author:

Papadaki Amalia¹,Politou Anastasia S.²³,Smirlis Despina⁴,Kotini Maria P.¹,Kourou Konstadina²,Papamarcaki Thomais²³,Boleti Haralabia¹⁵

Affiliation:

1. Intracellular Parasitism Group, Department of Microbiology, Hellenic Pasteur Institute, Athens 11521, Greece

2. Laboratory of Biological Chemistry, Medical School, University of Ioannina, Ioannina 45110, Greece

3. Biomedical Research Division, Foundation for Research and Technology-Hellas, Institute of Molecular Biology and Biotechnology, Ioannina 45110, Greece

4. Molecular Parasitology Laboratory, Department of Microbiology, Hellenic Pasteur Institute, Athens 11521, Greece

5. Light Microscopy Unit, Hellenic Pasteur Institute, Athens 11521, Greece

Abstract

Acid ecto-phosphatase activity has been linked to Leishmania donovani virulence. In the present study, we confirm the molecular identity and characterize molecular and functional properties of an enzyme contributing to this activity, the LdMAcP, an L. donovani specific membrane histidine acid phosphatase (HAcP).

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://portlandpress.com/biochemj/article-pdf/467/3/473/681884/bj4670473.pdf

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