1. 1Department of Pharmacological Sciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K.
2. 2Department of Pharmacological Sciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K.
3. 3Department of Pharmacological Sciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K.
4. 4Department of Pharmacological Sciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U.K.