Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature-Reference-Cited by-同舟云学术

Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature

Published:1985-01-01 Issue:s10 Volume:68 Page:121s-123s
ISSN:0144-9664
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Vanhoutte P. M.¹,Cooke J. P.¹,Lindblad L.-E.¹,Shepherd J. T.¹,Flavahan N. A.¹

Affiliation:

1. Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, U.S.A.

Abstract

1. In canine cutaneous veins, local moderate warming (37°-41°C) augments the responsiveness to postjunctional α1-adrenergic stimulation but depresses that to postjunctional α2-adrenergic activation. Moderate cooling (37°-24°C) has the opposite effect. 2. The effects of warming and cooling on α1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α2-adrenergic responsiveness.

Publisher

Portland Press Ltd.

Subject

Ocean Engineering

Link

https://portlandpress.com/clinsci/article-pdf/68/s10/121s/754979/cs068s121.pdf

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