Evolution of moonlighting proteins: insight from yeasts

Author:

Gancedo Carlos1,Flores Carmen-Lisset1,Gancedo Juana M.1

Affiliation:

1. Department of Metabolism and Cell Signalling. Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC-UAM, Madrid E-28029, Spain

Abstract

The present article addresses the possibilities offered by yeasts to study the problem of the evolution of moonlighting proteins. It focuses on data available on hexokinase from Saccharomyces cerevisiae that moonlights in catabolite repression and on galactokinase from Kluyveromyces lactis that moonlights controlling the induction of the GAL genes. Possible experimental approaches to studying the evolution of moonlighting hexose kinases are suggested.

Publisher

Portland Press Ltd.

Subject

Biochemistry

Reference50 articles.

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