A comparison of seven methods for fitting the Michaelis-Menten equation

Author:

Atkins G L1,Nimmo I A1

Affiliation:

1. Department of Biochemistry, University Medical School, Teviot Place, Edinburgh EH8 9AG, U.K.

Abstract

The Michaelis-Menten equation was fitted to simulated data containing different sorts of error by using the three linear transformations, and the methods of S. R. Cohen [Anal. Biochem. (1968) 22, 549-552], R. Eisenthal & A. Cornish-Bowden [Biochem. J. (1974) 139, 715-120], F. de M. Merino [Biochem. J.143, 93-95] and G. N. Wilkinson [Biochem. J. (1961) 80, 324-332). The best methods were those of Eisenthal & Cornish-Bowden (1974) and Wilkinson (1961).

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry

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