The Relationship between Concentrations of Glycosylated Haemoglobins and of Serum High-Density-Lipoprotein Cholesterol in Diabetic Patients

Author:

Yudkin J. S.1,Boucher B. J.1,France M. W.2,Welch S. G.,Swindlehurst C.3

Affiliation:

1. Metabolic and Endocrine Unit, London Hospital Medical College, London E.1, London

2. Department of Clinical Chemistry, London Hospital, London

3. Department of Biochemistry, London Hospital Medical College, London E.1, London

Abstract

1. Concentrations of high-density-lipoprotein cholesterol and of glycosylated haemoglobins [HbA1(a+b+c)] were measured in non-fasting blood samples taken from 171 diabetic patients. 2. Mean concentrations of high-density-lipoprotein cholesterol were lower in men, and in patients not requiring insulin. 3. There was no correlation between concentrations of high-density-lipoprotein cholesterol and of HbA1(a+b+c) in the patients as a whole, but a significant positive correlation was found between these values in male diabetics not requiring insulin. 4. Changes in the concentrations of HbA1(a+b+c) were not correlated with changes in concentrations of high-density-lipoprotein cholesterol.

Publisher

Portland Press Ltd.

Subject

General Medicine

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