Changes in the Carotid Body and the Ventilatory Response to Hypoxia in Chronically Hypoxic Rats-Reference-Cited by-同舟云学术

Changes in the Carotid Body and the Ventilatory Response to Hypoxia in Chronically Hypoxic Rats

Published:1976-04-01 Issue:4 Volume:50 Page:311-313
ISSN:0301-0538
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Barer Gwenda R.¹²,Edwards C. W.¹²,Jolly Angela I.¹²

Affiliation:

1. Section of Experimental Medicine, Academic Division of Medicine, University of Sheffield, U.K.

2. Department of Pathology, University of Liverpool, U.K.

Abstract

1. Young rats were kept in a hypoxic chamber for 2–11 weeks and compared with littermate control animals. 2. The carotid bodies of the hypoxic rats enlarged, resembling those of men and animals living at high altitude. 3. Permanent blunting of the ventilatory response to hypoxia did not occur. Immediately on removal from the chamber, the rats, lightly anaesthetized, showed a smaller increase in ventilation during hypoxia than did control animals but this difference disappeared after 3 days' recovery in normoxia.

Publisher

Portland Press Ltd.

Subject

General Medicine

Link

http://portlandpress.com/clinsci/article-pdf/50/4/311/816347/cs0500311.pdf

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