Affiliation:
1. Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, U.K.
Abstract
Between spring 1982 and autumn 1984 the physiological role of Ins(1,4,5)P3 as a calcium-mobilizing second messenger was first suggested and then experimentally established. At the same time the unexpected complexity of inositide metabolism began to be exposed by the discovery of Ins(1,3,4)P3. This article recalls my entanglement with these two inositol phosphates.
Reference53 articles.
1. Timeline: 20 years of Ins(1,4,5)P3, and 40 years before;Irvine;Nat. Rev. Mol. Cell. Biol.,2003
2. Back in the water: the return of the inositol phosphates;Irvine;Nat. Rev. Mol. Cell Biol.,2001
3. Synthesis and function of 3-phosphorylated inositol lipids;Vanhaesebroeck;Annu. Rev. Biochem.,2001
4. Xylitol or bust;Irvine;trp3 (Wellcome News),1997
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