Experimental Studies on the Mechanism of Adrenocorticotrophic Hormone-Induced Hypertension in the Sheep-Reference-Cited by-同舟云学术

Experimental Studies on the Mechanism of Adrenocorticotrophic Hormone-Induced Hypertension in the Sheep

Published:1973-08-01 Issue:s1 Volume:45 Page:269s-271s
ISSN:0144-4107
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Scoggins B. A.¹,Coghlan J. P.²,Cran Elizabeth J.³,Denton D. A.⁴,Fan S. K.⁵,McDougall J. G.⁶,Oddie Catherine J.⁷,Robinson P. M.⁸,Shulkes A. A.⁹

Affiliation:

1. 1Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

2. 2Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

3. 3Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

4. 4Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

5. 5Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

6. 6Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

7. 7Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

8. 8Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

9. 9Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, Victoria, Australia

Abstract

1. The mechanism of adrenocorticotrophic hormone (ACTH)-induced hypertension in the sheep has been examined. 2. Hypertension was dependent on the presence of the adrenal gland. 3. ACTH-hypertension was not reproduced by administration of cortisol, corticosterone, deoxycorticosterone or deoxycortisol, alone or in combination. 4. Intact adrenal nerves were not necessary for the hypertension. 5. It is postulated that an adrenal factor other than those studied may be responsible for the hypertension.

Publisher

Portland Press Ltd.

Subject

General Medicine

Link

http://portlandpress.com/clinsci/article-pdf/45/s1/269s/831179/cs045269s.pdf

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The effect of ACTH on the blood clearance rate of aldosterone, cortisol, 17α-hydroxyprogesterone and 17α,20α-dihydroxy-4-pregnen-3-one in the sheep;Journal of Steroid Biochemistry;1983-02

2. THE EFFECT OF ADRENAL DENERVATION ON ACTH-INDUCED HYPERTENSION IN SHEEP;Clinical and Experimental Pharmacology and Physiology;1974-12