Author:
Onishi S,Isobe K,Itoh S,Kawade N,Sugiyama S
Abstract
Photobilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant was demonstrated for the first time by reversed-phase high-pressure liquid chromatography. The concentrations increased significantly during phototherapy. Corresponding to these changes in the serum, biliary unconjugated bilirubin concentrations increased markedly but photobilirubin-IX alpha was not detected in the bile. Moreover, large amounts of ‘unknown pigment’ that are diazo-negative appeared in the bile during phototherapy.
Subject
Cell Biology,Molecular Biology,Biochemistry
Cited by
77 articles.
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