Enhanced distal absorption of potassium by magnesium-deficient rats

Author:

Wong Norman L. M.1,Sutton Roger A. L.1,Mavichak Viroon1,Quamme Gary A.1,Dirks John H.1

Affiliation:

1. Department of Medicine, Health Sciences Centre Hospital, University of British Columbia, Vancouver, British Columbia, Canada

Abstract

1. The effect of acute potassium infusion on renal tubular reabsorption of potassium by magnesium-deficient and pair-fed control rats has been studied by the recollection micropuncture method. 2. During potassium chloride infusion, the amount of potassium remaining in the distal tubule is lower in magnesium-deficient than in pair-fed rats. This could be due to a reduction in potassium secretion or to an enhancement of potassium reabsorption. 3. The present study demonstrates enhanced renal potassium retention in the magnesium-deficient rat, and is in contrast to previous reports of renal potassium wasting in this circumstance.

Publisher

Portland Press Ltd.

Subject

General Medicine

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