Affiliation:
1. Department of Medical Biochemistry, Sylvius Laboratories, Leiden, The Netherlands.
Abstract
Damage to DNA caused by exposure of L929 fibroblasts to ozone was reflected by the generation of strand breaks, DNA inter-strand cross-links and DNA-protein cross-links. Addition of propan-2-ol, a hydroxyl radical scavenger, did not affect the formation of strand breaks. In model experiments it appeared that both purines and pyrimidines were involved in DNA inter-strand and DNA-protein cross-links.
Subject
Cell Biology,Molecular Biology,Biochemistry
Cited by
17 articles.
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