Therapeutic strategies to target microbial protein–glycosaminoglycan interactions-Reference-Cited by-同舟云学术

Therapeutic strategies to target microbial protein–glycosaminoglycan interactions

Published:2018-10-31 Issue:6 Volume:46 Page:1505-1515
ISSN:0300-5127
Container-title:Biochemical Society Transactions
language:en
Short-container-title:

Author:

Almer Johannes¹,Gesslbauer Bernd¹,Kungl Andreas J.¹²

Affiliation:

1. Karl Franzens University Graz, Institute of Pharmaceutical Sciences, Schubertstrasse 1, 8010 Graz, Austria

2. Antagonis Biotherapeutics GmbH, Strasserhofweg 77a, 8045 Graz, Austria

Abstract

Glycans are involved in a plethora of human pathologies including infectious diseases. Especially, glycosaminoglycans (GAGs), like heparan sulfate and chondroitin sulfate, have been found to be involved in different crucial stages of microbial invasion. Here, we review various therapeutic approaches, which target the interface of host GAGs and microbial proteins and discuss their limitations and challenges for drug development.

Publisher

Portland Press Ltd.

Subject

Biochemistry

Link

https://portlandpress.com/biochemsoctrans/article-pdf/46/6/1505/482223/bst-2017-0485c.pdf

Reference97 articles.

1. World Health Organization (2017) Monitoring Health for the SDGs, Sustainable Development Goals, World Health Organization, Geneva

2. Carbohydrate-related inhibitors of dengue virus entry;Hidari;Viruses,2013

3. Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells;Coppi;Cell Host Microbe,2007

4. Glycosaminoglycans in infectious disease;Kamhi;Biol. Rev.,2013

5. Diverse Functions of Glycosaminoglycans in Infectious Diseases

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