ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

Author:

Touyz Rhian M.1ORCID,Li Hongliang2,Delles Christian1ORCID

Affiliation:

1. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, U.K.

2. Department of Cardiology, Renmin Hopsital of Wuhan University, Institute of Model Animal of Wuhan University, Wuhan, China

Abstract

Abstract Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.

Publisher

Portland Press Ltd.

Subject

General Medicine

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