Multifunctional neuron-specific enolase: its role in lung diseases-Reference-Cited by-同舟云学术

Multifunctional neuron-specific enolase: its role in lung diseases

Published:2019-11 Issue:11 Volume:39 Page:
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Xu Cai-Ming¹²,Luo Ya-Lan¹,Li Shuai³,Li Zhao-Xia¹,Jiang Liu¹,Zhang Gui-Xin¹,Owusu Lawrence¹⁴,Chen Hai-Long¹^ORCID

Affiliation:

1. Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian 116011, Liaoning, China; Institute (College) of Intergrative Medicine, Dalian Medical University, Dalian 116044, Liaoning, China

2. Department of Traditional Chinese Medicine, Dalian Obstetrics and Gynecology Hospital, Dalian 116021, Liaoning, China

3. Department of Pediatric Orthopedics, Qingdao Women and Children’s Hospital, Qingdao 266035, Shandong, China

4. Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), PMB, UPO, Kumasi, Ghana

Abstract

Abstract Neuron-specific enolase (NSE), also known as gamma (γ) enolase or enolase-2 (Eno2), is a form of glycolytic enolase isozyme and is considered a multifunctional protein. NSE is mainly expressed in the cytoplasm of neurons and neuroendocrine cells, especially in those of the amine precursor uptake and decarboxylation (APUD) lineage such as pituitary, thyroid, pancreas, intestine and lung. In addition to its well-established glycolysis function in the cytoplasm, changes in cell localization and differential expression of NSE are also associated with several pathologies such as infection, inflammation, autoimmune diseases and cancer. This article mainly discusses the role and diagnostic potential of NSE in some lung diseases.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/doi/10.1042/BSR20192732/860409/bsr-2019-2732.pdf

Reference133 articles.

1. Molecular evolution of enolase;Piast;Acta Biochim. Pol.,2005

2. Enolase from Trypanosoma brucei, from the amitochondriate protist Mastigamoeba balamuthi, and from the chloroplast and cytosol of Euglena gracilis: pieces in the evolutionary puzzle of the eukaryotic glycolytic pathway;Hannaert;Mol. Biol. Evol.,2000

3. Exploring non-metabolic functions of glycolytic enzymes in immunity;Seki;Front. Immunol.,2017

4. alpha-Enolase: a promising therapeutic and diagnostic tumor target;Capello;FEBS J.,2011

5. Enolase isoenzymes. II. Hybridization studies, developmental and phylogenetic aspects;Rider;Biochim. Biophys. Acta,1975

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