Retained folates in the rat-Reference-Cited by-同舟云学术

Retained folates in the rat

Published:1977-06-15 Issue:3 Volume:164 Page:601-605
ISSN:0264-6021
Container-title:Biochemical Journal
language:en
Short-container-title:

Author:

Barford P A,Staff R J,Blair J A

Abstract

The retention of radioactivity after doses of 14C- and 3H-labelled folic acid is described. Radioactivity was retained in liver, kidney and gut of rats for some time after administration of the dose. The retained radioactivity could not be displaced by large doses of unlabelled folic acid or unlabelled 5-methyltetrahydrofolate. 14C- and 3H-labbelled folates showed similar chromatographic behaviour onion-exchange chromatography to 5-methyltetrahydrofolate, and on ion-exchange and gel-permeation chromatography to synthetic pteroylhepta-gamma-glutamate.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://portlandpress.com/biochemj/article-pdf/164/3/601/568957/bj1640601.pdf

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1. The fate of [3H]folic acid in folate-adequate rats;The Journal of Nutritional Biochemistry;1996-05

2. Improving the response of the rat liver folate bioassay;The Journal of Nutritional Biochemistry;1991-06

3. Determination of mouse liver 5-methyltetrahydrofolate concentration and polyglutamate forms;Journal of Biochemical and Biophysical Methods;1985-03

4. Effects of phenobarbitone and phenytoin on folate catabolism in the rat;Biochemical Pharmacology;1983-11

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