Membrane cholesterol and the regulation of signal transduction-Reference-Cited by-同舟云学术

Membrane cholesterol and the regulation of signal transduction

Published:2004-02-01 Issue:1 Volume:32 Page:65-69
ISSN:0300-5127
Container-title:Biochemical Society Transactions
language:en
Short-container-title:

Author:

Fielding C.J.¹,Fielding P.E.²

Affiliation:

1. Cardiovascular Research Institute and Department of Physiology, University of California, San Francisco, CA 94143, U.S.A.

2. Department of Medicine, University of California, San Francisco, CA 94143, U.S.A.

Abstract

The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent evidence suggests that transient changes in cholesterol content may be important in regulating signal transduction.

Publisher

Portland Press Ltd.

Subject

Biochemistry

Link

https://portlandpress.com/biochemsoctrans/article-pdf/32/1/65/531690/bst0320065.pdf

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