1. Department of Clinical Biochemistry and Metabolic Medicine, University of Newcastle upon Tyne Medical School, Newcastle upon Tyne NE1 4LP and NE1 7RU, U.K.
2. Department of Pharmacological Sciences, University of Newcastle upon Tyne Medical School, Newcastle upon Tyne NE1 4LP and NE1 7RU, U.K.
3. Department of Neurology, University of Newcastle upon Tyne Medical School, Newcastle upon Tyne NE1 4LP and NE1 7RU, U.K.