Affiliation:
1. Harry Powell Crystallographic, Buxton Road, Chingford, London E4 7DP, U.K.
Abstract
The method of molecular structure determination by X-ray crystallography is a little over a century old. The history is described briefly, along with developments in X-ray sources and detectors. The fundamental processes involved in measuring diffraction patterns on area detectors, i.e. autoindexing, refining crystal and detector parameters, integrating the reflections themselves and putting the resultant measurements on to a common scale are discussed, with particular reference to the most commonly used software in the field.
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
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