A Comparison of Chromium Sesquioxide and [51Cr]Chromic Chloride as Inert Markers in Calcium Balance Studies-Reference-Cited by-同舟云学术

A Comparison of Chromium Sesquioxide and [51Cr]Chromic Chloride as Inert Markers in Calcium Balance Studies

Published:1979-07-01 Issue:1 Volume:57 Page:89-92
ISSN:0143-5221
Container-title:Clinical Science
language:en
Short-container-title:

Author:

Hesp R.¹,Williams D.²,Rinsler M.³,Reeve J.⁴

Affiliation:

1. 1Divisions of Radioisotopes and Clinical Chemistry, MRC Clinical Research Centre and Northwick Park Hospital, Harrow, Middlesex, U.K.

2. 2Divisions of Radioisotopes and Clinical Chemistry, MRC Clinical Research Centre and Northwick Park Hospital, Harrow, Middlesex, U.K.

3. 3Divisions of Radioisotopes and Clinical Chemistry, MRC Clinical Research Centre and Northwick Park Hospital, Harrow, Middlesex, U.K.

4. 4Divisions of Radioisotopes and Clinical Chemistry, MRC Clinical Research Centre and Northwick Park Hospital, Harrow, Middlesex, U.K.

Abstract

1. Chromium sesquioxide (Cr2O3; 1·5 g/day) and [51Cr]chromic chloride [31CrCl3 (0·3 μCi/day)] were compared as continuously administered non-absorbed markers for the correction of faecal recoveries in 14 calcium balance studies each lasting at least 18 days. 2. The mean recoveries of each, 98·4% for Cr2O3 and 101·9% for 51CrCl3, were not significantly different from 100. 3. The two markers reduced the uncertainty in a typical 3 × 6 day calcium balance study to a similar extent (sd = 1·4 mmol/day for Cr2O3 and sd = 1·5 mmol/day for 51CrCl3). 4. 5lCrCl3 is a convenient and satisfactory alternative to Cr2O3 when the laboratory hazards associated with estimating the latter cannot easily be eliminated.

Publisher

Portland Press Ltd.

Subject

General Medicine

Link

https://portlandpress.com/clinsci/article-pdf/57/1/89/451942/cs0570089.pdf

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