The differentiation courses of the Tfh cells: a new perspective on autoimmune disease pathogenesis and treatment-Reference-Cited by-同舟云学术

The differentiation courses of the Tfh cells: a new perspective on autoimmune disease pathogenesis and treatment

Published:2024-01 Issue:1 Volume:44 Page:
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Yang Qingya¹,Zhang Fang²³,Chen Hongyi²³,Hu Yuman²³,Yang Ning²³,Yang Wenyan²³,Wang Jing²³,Yang Yaxu²³,Xu Ran²³,Xu Chao²³^ORCID

Affiliation:

1. 3Division of Rheumatology, People’s Hospital of Mianzhu, Mianzhu, Sichuan, 618200, China

2. 1Division of Rheumatology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210028, China

3. 2Division of Rheumatology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu 210028, China

Abstract

Abstract The follicular helper T cells are derived from CD4+T cells, promoting the formation of germinal centers and assisting B cells to produce antibodies. This review describes the differentiation process of Tfh cells from the perspectives of the initiation, maturation, migration, efficacy, and subset classification of Tfh cells, and correlates it with autoimmune disease, to provide information for researchers to fully understand Tfh cells and provide further research ideas to manage immune-related diseases.

Funder

Jiangsu Provincial Traditional Chinese Medicine Science and Technology Development Plan Project

Youth Natural Science Foundation of Jiangsu Province

Natural Science Foundation of Nanjing University of Chinese Medicine

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/doi/10.1042/BSR20231723/953803/bsr-2023-1723.pdf

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