Amino acid sequence of the encephalitogenic basic protein from human myelin-Reference-Cited by-同舟云学术

Amino acid sequence of the encephalitogenic basic protein from human myelin

Published:1971-06-01 Issue:1 Volume:123 Page:57-67
ISSN:0306-3283
Container-title:Biochemical Journal
language:en
Short-container-title:

Author:

Carnegie P. R.¹

Affiliation:

1. Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, Vic. 3052, Australia

Abstract

Myelin from the central nervous system contains an unusual basic protein, which can induce experimental autoimmune encephalomyelitis. The basic protein from human brain was digested with trypsin and other enzymes and the sequence of the 170 amino acids was determined. The localization of the encephalitogenic determinants was described. Possible roles for the protein in the structure and function of myelin are discussed.

Publisher

Portland Press Ltd.

Link

https://portlandpress.com/biochemj/article-pdf/123/1/57/770811/bj1230057.pdf

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