Tools for the cryo-EM gold rush: going from the cryo-EM map to the atomistic model-Reference-Cited by-同舟云学术

Tools for the cryo-EM gold rush: going from the cryo-EM map to the atomistic model

Published:2017-12-05 Issue:6 Volume:37 Page:
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Kim Doo Nam¹,Sanbonmatsu Karissa Y.¹²

Affiliation:

1. Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, U.S.A.

2. New Mexico Consortium, Los Alamos, U.S.A.

Abstract

As cryo-electron microscopy (cryo-EM) enters mainstream structural biology, the demand for fitting methods is high. Here, we review existing flexible fitting methods for cryo-EM. We discuss their importance, potential concerns and assessment strategies. We aim to give readers concrete descriptions of cryo-EM flexible fitting methods with corresponding examples.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/doi/10.1042/BSR20170072/808396/bsr-2017-0072c.pdf

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