Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα
Author:
Affiliation:
1. AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, U.K.
2. Pepscan Presto, Zuidersluisweg 2, 8243 RC Lelystad, The Netherlands
3. ExSAR, 11 Deer Park Drive, Suite 103, Monmouth Junction, NJ 08852, U.S.A.
Abstract
Publisher
Portland Press Ltd.
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Link
https://portlandpress.com/bioscirep/article-pdf/doi/10.1042/BSR20130044/476156/bsr033e060.pdf
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3. Cytokines and anticytokines in the pathogenesis of sepsis;van der Poll;Infect Dis. Clin. North Am.,1999
4. Development of anti-TNF therapy for rheumatoid arthritis;Feldmann;Nat. Rev. Immunol.,2002
5. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review;Tracey;Pharmacol. Ther.,2008
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