The number and location of genes for 5S ribonucleic acid within the genome of Drosophila melanogaster-Reference-Cited by-同舟云学术

The number and location of genes for 5S ribonucleic acid within the genome of Drosophila melanogaster

Published:1971-06-01 Issue:2 Volume:123 Page:227-233
ISSN:0306-3283
Container-title:Biochemical Journal
language:en
Short-container-title:

Author:

Quincey R. V.¹

Affiliation:

1. Department of Biochemistry, Dartmouth Medical School, Hanover, N.H. 03755, U.S.A. and Department of Chemical Pathology, King's College Hospital Medical School, London S.E.5, U.K.

Abstract

DNA was prepared from wild-type and two mutant stocks of Drosophila melanogaster that differed in their dosage of the nucleolar organizer region. The relative amounts of DNA from the nucleolar organizer region in these preparations of DNA were determined by hybridization with 3H-labelled 28S rRNA. As expected, the amount of 3H-labelled 28S rRNA that hybridized was directly related to the dosage of nucleolar organizer region. No positive correlation was observed between the amount of 3H-labelled 5S RNA that hybridized and the dosage of nucleolar organizer region. Thus genes for 5S RNA are located primarily, if not exclusively, outside the nucleolar organizer region. The haploid genome of the wild-type D. melanogaster used in this work has 106 genes for 28S rRNA and 96–105 genes for 5S RNA.

Publisher

Portland Press Ltd.

Link

https://portlandpress.com/biochemj/article-pdf/123/2/227/771032/bj1230227.pdf

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