The Analysis of Urological Morbidity in HIV-Infected Patients of the Vladivostok City District

Abstract

Introduction: HIV infection, the disease that develops as a result of infection with the human immunodeficiency virus, has moved from the category of fatal diseases to indolent manageable infections. Urologic diseases are a common complication observed already in the early stages of HIV infection, and the prevalence of kidney disease in HIV patients ranges from 5% to 30%. Our objective was to analyze urological morbidity in HIV-infected patients hospitalized for emergency and planned indications in the Urology Department of Vladivostok Clinical Hospital No. 2 (VCB No. 2) and to identify the main nosological forms of urological pathology in this cohort. Methods: For the analysis of epidemiological, immunological and virological characteristics of 91 HIV-infected patients admitted to the Urology Department from June 2016 to December 2019 we reviewed inpatient and outpatient medical histories, structured HIV-infected patients by urological nosologies, assessed stages of HIV infection and values of viral load and CD4+ T-lymphocytes, and established the presence of coinfections. Results: The analysis revealed the prevalence of acute infectious and inflammatory diseases of the urinary system (pyelonephritis, prostatitis, orchiepidymitis, kidney abscess) and urolithiasis, which in some cases required the immediate initiation of empirical antibiotic therapy and emergency drainage of the renal cavity system. Our findings are consistent with the results of studies previously conducted on a different population of HIV-infected patients. Conclusions: Since the Urology Department of Vladivostok Clinical Hospital No. 2 is the main hospital that provides both emergency and planned urology care, our data fully reflect urological morbidity of HIV-infected patients in the city district and can be used for optimization of medical care for this cohort of patients.