Creation of Databases for Systematization of Antibiotic Resistance Monitoring Results

Abstract

Introduction: The study of the composition and antibiotic resistance of bacterial communities of water bodies requires effective processing of numerous data. Our objective was to systematize studies of sensitivity/resistance of pathogenic and opportunistic microorganisms in water reservoirs of Rostov-on-Don and the Rostov Region conducted by the Rostov-on-Don Anti-Plague Research Institute and to create databases (DB) including epidemiological information on the date and source of an isolate, results of bacterial strain identification, and evaluation of their sensitivity/resistance to antibacterial preparations (ABP). Materials and methods: Isolation, identification and interpretation of results of determining sensitivity/resistance to antibacterial preparations were carried out for different groups of microorganisms using standard techniques. Results: The databases “Phenotypes of antibiotic resistance of Vibrio cholerae of various serogroups isolated in the Rostov Region” (2017621303 dated November 14, 2017) and “Spectrum of microflora of open reservoirs in Rostov-on-Don, sensitivity/resistance to antibacterial drugs” (2017620158 dated February 28, 2017) were registered. The article describes the experience in creating and using the databases to process and analyze research results. The databases are regularly supplemented and updated as part of annual monitoring enabling us not only to monitor and analyze large amounts of heterogeneous information, but also to quickly compare the data, analyze sensitivity/resistance of microorganisms of different groups to a wide range of ABP, and visualize the results.