Abstract
Introduction: A steady increase in the incidence of malignant neoplasms was registered in the Primorsky Region in 2009–2019 with the rate rising by 26.1 %. The statistical analysis of the relationship between quality of life indicators and disease contributes to identifying significant risk factors, the consideration of which will improve the set of measures aimed at promoting a healthy lifestyle and encouraging regular medical checkups in order to reduce cancer incidence and mortality rates.
Objective: To establish external carcinogenic risk factors in the Primorsky Region.
Materials and methods: The study was conducted based on statistical data from the local offices of the Federal Service for State Statistics and the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing for 2007–2019. We
did correlation and regression analyses of the collected information and applied the principal component analysis to reduce dimensionality of the data. Results: The statistical data analysis revealed the principal components and their association with the incidence of malignant neoplasms of five sites in the Primorsky Region.
Conclusion: In addition to genetic predispositions, the lifestyle strongly contributes to the development of cancer, which must be taken into account when elaborating appropriate preventive measures at the regional level.
Publisher
Federal Center for Hygiene and Epidemiology
Subject
Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science
Reference20 articles.
1. World Health Organization. Cancer. February 3, 2022 [online resource]. Accessed: June 24, 2022. http:// www.who.int/ru/news-room/fact-sheets/detail/cancer
2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):7-30. doi: 10.3322/ caac.21590
3. Prasad V. Our best weapons against cancer are not magic bullets. Nature. 2020;577(7791):451. doi: 10.1038/ d41586-020-00116-2
4. Parkin DM, Boyd L, Walker LC. 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010. Br J Cancer. 2011;105(Suppl 2):S77-81. doi: 10.1038/bjc.2011.489
5. Nurmanova A, Sultanova ZI, Anaorazov YA. Factors and their role in morbidity, mortality, survival in mammary cancer. Vestnik Kazakhskogo Natsional’nogo Meditsinskogo Universiteta. 2018;(1):112-114. (In Russ.)