Prevalence of Hyperuricemia In Acute Ischemic Stroke Patients: A Cross-Sectional Study

Abstract

Ischemic stroke is responsible for a significant proportion of stroke cases, with stroke being a major contributor to mortality and morbidity on a global scale. Objective: To check the relation of hyperuricemia with stroke. Methods: A cross-sectional study was carried out in the Jinnah Post-graduate Medical Center's Medicine ward more than six months after the acceptance of the synopsis. This study was conducted between 2020 and 2021. The sample size for the study was determined to be at least 94. Non-probability consecutive sampling was employed to select patients aged >20 years, of either sex, who were diagnosed with acute ischemic stroke. Patients with ischemic stroke due to a known thrombophilic condition and those with hyperuricemia secondary to high cell turnover from cancer chemotherapy were excluded from the study. The frequencies and percentages were collected and calculated and chi-square was used to evaluate the significance. The p-value of <0.005 was considered significant. Results: We enrolled 94 patients in total. Table 1 shows the demographics of the patients who presented to the hospital. The most common age group was >60 years and the majority of the patients were male (61.7%). The 51 (54.2%) patients have a BMI >25. 65 (69.1%) of the patients had diabetes. The relationship between the patients with hyperuricemia with the male gender, hypertensive patients, and patients who smoke with a p-value of <0.001. Conclusions: In conclusion, hyperuricemia appears to be prevalent in acute ischemic stroke patients, especially among the elderly population.