Effect of Age on Survival in Patients with Cervical Cancer

Abstract

Cervical cancer survival rates depend on several factors, such as the stage of the cancer, age of the patient, and overall health status. However, early detection through regular screening and prompt treatment can significantly increase the chances of survival. Objectives: To determine the effects of age and other prognostic factors on survival in patients with cervical cancer. Methods: The medical records of 142 patients with cervical cancer were retrospectively reviewed. All patients were diagnosed by biopsy between January 2000 and December 2012 at the Princess Norah Oncology Center of King Abdul Aziz Medical City (Jeddah, Saudi Arabia). Kaplan-Meier survival curves and log-rank tests were used to compare groups. Results: The mean age at diagnosis was 51.77 ± 13.36 years (range, 28–96 years). The 1-year survival rates for each age group were as follows: < 30 years, 100%; 30–54 years, 83.9%; 55–65 years, 72.2%; and > 65 years, 73.3%. By contrast, the 5-year survival rates (0%, 38.5%, 30.8%, and 33%, respectively) were much lower. No significant differences in survival outcomes were identified among the age groups. Low mean hemoglobin levels during treatment were associated with poor survival rates. The mean hemoglobin level for all patients was 14.22 ± 16.28 mg/dL. Conclusions: Survival outcomes in patients with cervical cancer were not influenced by age at diagnosis. It will be necessary to perform systematic reviews of multiple studies on this topic to come to a more definitive conclusion.