Effect of Moringa Olifera Leaves on Intraocular Pressure and Blood Pressure

Abstract

Moringa exhibits many antioxidant, antihypertensive, and anticancer effects. A significant source of therapeutic medicines for reducing ocular and systemic hypertension is herbal remedies. Objectives: To assess the impact of moringa on blood pressure and intraocular pressure and to evaluate various moringa doses that affect IOP and BP. Methods: Quasi Experimental study was conducted at MTH, Faisalabad from September 2022 to April 2023. Sampling technique was non-probability purposive sampling. Emmetropes, age 20-35 years, IOP range 11-22 mmHg, BP 120/80 mmHg was included. After comprehensive eye exam, 60 subjects were divided into two groups. IOP and BP were evaluated before and after intake at 30, 60, 90, and 120 minutes. Data were analyzed with SPSS software. Repeated Measure ANOVA was used for statistical analysis. Results: Out of 60 subjects, mean age was 22.5 ± 1.31. Baseline IOP in group 1 was 19.40 ± 3.19 and BP 113.67 ± 9.27/81.00 ± 8.03 while in group 2 IOP 19.42 ± 4.11 and BP 116.33 ± 10.08/83.17 ± 8.75. There was significant Change in IOP at 90minutes and BP at 60minutes. IOP was 18.54 ± 3.19 and 17.56 ± 4.25 in group 1, 2 respectively. BP was 101.33 ± 7.76/72.67 ± 8.97 and 101.50 ± 9.92/72.50 ± 8.68 in both groups respectively. There were significant Changes as compared to 30, 60, 120minutes. IOP and BP return to its baseline at 120 minutes. Conclusions: Moringa Oleifera has significant effect on lowering IOP and BP. Effect of dose on the reduction rate was directly proportional to the amount of dose administered.