Comparison of Frequency of Pathogenic Micro-Organisms Causing Bloodstream Infections in Patients Admitted at Tertiary Care Hospital Rawalpindi

Abstract

Blood Stream Infections (BSI) are frequently occurring thing in hospital setting and if not tested and appropriate medicine not used, it has significant mortality and also adds an extra burden on health care. Objective: To find the frequency of various pathogenic micro-organisms causing bloodstream infections. Methods: Cross-sectional study was done in tertiary Care Hospital Rawalpindi from April 23 to August 23. Blood samples of 50 patients from two age groups were collected (n=25 above 60 years and n=25 ages 30-60 years). Blood samples were drawn into glass vial containing 20% EDTA to prevent blood clotting and then culture studies were performed. Results: Mean participant age in both study groups was 75.76 ± 8.9 and 46.88 ± 7.7 years (p<0.001). Blood culture analysis revealed that 42 isolates of Staphylococcus aureus was present in >60 years of patients and 55 isolates of Staphylococcus aureus were present in 30-60 years age group.  255 isolates of Escherichia coli. was present in >60 years’ patients and 312 isolates of Escherichia coli were present in 30-60 years’ age group. 9 isolates of Klebsiella was present in >60 years patients and 05 isolates of Klebsiella were present in 30-60 years age group years. Conclusions: Study showed that significant number of microorganism were present in collected blood culture samples. Among various strains of microorganisms, most common is Escherichia coli. Followed by Staphylococcus aureus. Study also highlights that BSI is a frequent occurring problem in hospital setting and if proper antibiotic administered, early cure can be achieved.