Spectrum Of Antimicrobial Susceptibility Pattern of Urinary Tract Infection in In Adults

Abstract

Patients of all ages and genders regularly experience urinary tract infections. Antibiotic misuse has caused organisms to develop drug resistance, creating a treatment problem. Objective: To uncover risk variables and relationships, as well as the antibiotic susceptibility in UTI patients. Methods: Diabetes and non-diabetes with UTI were compared within groups using the Chi-square test, with a significant P-value of 0.05. Results: 32 (21.2%) were given empirical treatment with ciprofloxacin (11%), cefixime (5%), ceftriaxone (2.6%), cefoparazone-sulbactum (1.30%), amoxicillin-clavulanic acid (1.30%), ampicillin (1.30%), and co-trimoxazole (0.60%), respectively. E. coli was the most prevalent pathogen, with an isolation rate of 84%, followed by pseudomonas aeruginosa (6%), Serratia (3.3%), klebsiella (2.6%), Enterobacter cloacae (2.6%), Sternotophomus (0.7%), and MRSA (each in 0.7%). Ampicillin, Cefixime, Ceftriaxone, Co-Trimoxazole, Ciprofloxacin, Amoxicillin-Clavulanic Acid, Tetracycline, and Levofloxacin were all often resistant to, respectively, 87 percent, 83 percent, 78 percent, 78 percent, and 51 percent of these antibiotics. Conclusions: MDR prevalence is highest in gram-negative bacteria. The presence of diabetes mellitus and being a woman are significant risk factors for UTI, according to tests. Escherichia coli (84%) is the most common uropathogen. Carbapenems, piperacillin-tazobactam, Amikacin, Gentamicin, and cefoparazone-sulbactam (parenteral) as well as Nitrofurantoin are the preferred empirical treatments (oral). Hospitals and the nation at large should constantly examine and reassess their antimicrobial policies.