Frequency of Hyperandrogenism in Young Women with Polycystic Ovarian Syndrome

Abstract

Polycystic ovary syndrome (PCOS) is the communal disorder of endocrinology in females of reproductive age. Objective: The purpose of the study was to govern the incidence of hyperandrogenism in young females with polycystic ovarian syndrome. Methods: Total 93 women of age 20 to 35 years with any parity and diagnosed patients of PCOS were included. All patients were assessed biochemically. Serum of testosterone and sex hormone binding globulin analysis was done randomly at any phase of menstrual cycle. Participants were followed in OPD. Free androgen index was calculated. Score more than 5 labeled as Hyperandrogenemia. Data were analyzed using SPSS version 21.0. Results: The mean age was 27.22±4.58 years, with range of 15(20–35) years. Age of 46(49.5%) patients was ≤27 years and age of 47(50.5%) patients was >27 years. 41 patients were married and 52 patients were unmarried. The mean parity was 1.41±0.94 with range of 4(0–4). Results of free androgen index score (FAI) showed that overall mean FAI was 7.80±5.82 with range of 32.60(0.80–33.40). Total 60 patients were found with hyperandrogenism. Among these patients the mean age was 26.93±4.68 years. Ages of 32(53.3%) patients were ≤27 years. participants it was observed that 18 patients were nulliparous, 3 patients had 1-2 parity, and 2 patients had parity more than 2. Chi square results for association of hyperandrogenism showed no significant association with age, marital status, and parity with p>0.05. Conclusion: Hyperandrogenism is an important feature of PCOS. It mainly comes from the ovaries of women diagnosed with PCOS. The best indicator of hyperandrogenism is Serum testosterone levels.