Anatomical Sites OF Superficial Basal Cell Cancers Demonstrate Higher Rates of Mixed Histology

Abstract

Historically, "aggressive" histologic subsets (HSs) of basal cell carcinoma (BCC) seem to be more likely to statistically exhibit Subclinical extension and require more phases during Mohs micrographic surgery (MMS) and consequently larger margins upon excision. The "Mohs Suitable Use Criteria (MAUC)" for the most appropriate therapy of superficial basal cell carcinoma. Objective: To evaluate if aggressive subtypes of superficial Basal Cell Carcinoma are common among healthy, immunocompromised patients and high-risk anatomical sites. Methods: The study was carried out in Khyber Teaching Hospital Peshawar, from November 2021-march to 2022, A total of 100 Mohs surgeries on superficial basal cell carcinoma were performed. Under light microscope slides were examined for any pattern of histology besides superficial basal cell carcinoma for statistical analysis MAU anatomical site healthy individuals and immunocompromised patients were grouped accordingly Results:  Among health and immunocompromised individuals’ zone H and zone L were significantly increased in mixed histology. While in healthy individuals’ the association between L Zone and M zone was incredibly significant but in immunocompromised was not significant Conclusions: The mixed histology of SBCC was higher in the head and neck region. Researchers say that the MAUC scoring technique for SBCC is supported by a high incidence in SBCC of the head and neck.