Role of glucose phosphate deficiency in neonatal hyperbilirubinemia among local population of Pakistan

Abstract

Due to the prevalence of new-born jaundice (65%) and neonatal hyperbilirubinemia (85%) in the first 24 hours of life, Objectives of the study: The study's main purpose is to investigate G6PD insufficiency in neonates. Material and methods: The Punjab Health Department conducted a descriptive study from July to December 2021. The hospital's ethics committee approved this probe. The research included 197 patients. The research included infants aged 0-20 days. A survey was used to collect data. Gender, gestational age, age of presentation, and length of hospitalisation were all noted. Results: The study included 197 patients, 61 of whom were female and 136 males. Participants in this research had bilirubin levels between 10 and 30 mg/dl. The maximum age in this study was 18 days, while the minimum was a new-born infant. G6DP insufficiency was seen in 21 of the 197 patients. 176 individuals had normal G6PD levels. Conclusion: The study found that G6PD deficiency is common in new-borns. Severe hyperbilirubinemia has several risk factors