Evaluating the effect of Ginger Powder on Bilirubin, Creatinine, Urea and Uric Acid on Experimental Diabetic Wistar Rats in Randomized Control Trial

Abstract

Today the world is dealing with rapidly increasing cases of diabetes mellitus especially type 2 diabetes which creates insulin resistance. Scientists are working with different nutraceuticals to cure this disease. Objective: Ginger plays an important role in different ailments such as cardiovascular diseases, hypertension, cancers, gastrointestinal functions, and diabetes mellitus. In the present study, ginger powder was analyzed for its anti-diabetic effect. The ginger powder was analyzed for its proximate composition. Methods: The bio-efficacy study was done on Alloxan-induced Wistar rats by feeding them ginger powder at three levels i.e. 1%, 3%, and 5% ginger powder for a period of 4 weeks. There were 4 groups (one was control and the other three getting different percentages of ginger powder), each containing 5 rats. The blood samples were collected at 0 days, 15th day, and 28th day. Blood sugar and insulin levels were measured. The data thus obtained was statistically analyzed to find out the level of significance. Results showed that glucose levels significantly decreased along with a significant increase in insulin levels. This research design concludes that ginger powder has positive effects in lowering blood sugar levels. Hence, the usage of ginger powder and ginger tea should be increased in diabetic patients to reduce hyperglycemia in diabetic patients and overcome high BSL levels in pre-diabetics. Conclusions: Results of this study concluded that in ginger powder 1.7 STD magnesium and 0.3 STD chromium are present. Moreover, this research study also declared that mean values of RFTs i.e. bilirubin, creatinine, urea, uric acid had a significant change in the G4 group as mean results of 0.591±0.032, 0.814±0.058, 0.814±0.058, 0.9508±0.051 respectively.