Influence of Phacoemulsification On Pre-Operative and Post-Operative Intraocular Pressure

Abstract

Various geographic regions have different ocular disease spectrums. It relies on the area's geographic position, economic situation, cultural diversity, and ethnic integrity. Visual impairment (VI) affects 624 million people worldwide, including 19 million children. Due to decreased productivity, blindness has a major financial impact on the individual, family, and society. Objectives: To compare the effect of phacoemulsification surgery and to determine the mean decrease in pupil size after instilling nepafenac 0.1% (preoperative IOP vs postoperative IOP). Methods: This study was conducted on 120 patients from period 2016-2017, who have given nepafenac 3 drops per day (steroid anti-inflammatory drops) one dayprior to surgery. The pupil size was measured with acaliper; immediately before (preoperative) and at the end of surgery (postoperative). The difference between pupillary diameters was noted and the decrease in pupil size was calculated. Results: The mean age was 52.53 ± 7.20 years in the given population. There were 42 (35%) males and females were 78 (65%).  The preoperative measurement of the pupil size was 7.13 ± 1.06 mm which was reduced to 6.27 ± 1.34 mm at end of surgery. The mean decrease in pupil size was 0.86 ± 0.46 mm. There was significant decrease in pupil size from baseline (preoperative) measurements than after the surgery (p <0.05). Conclusion: It is concluded that nepafenac 0.1% during phacoemulsification surgery can be beneficial in maintaining mydriasis in eyes of patients