Age, Gender and length of illness’s relation with Hepatic Dysfunction in individuals having Malaria: A cross-sectional study

Abstract

With almost 200 million medical cases occurring each year, malaria is the most common vector-borne disease worldwide. Objective: To ascertain the relationship of hepatic dysfunction with age, gender, and length of illness in individuals with malaria. Methods: Data were gathered using a non-probability consecutive sampling method. A total of 270 patients are selected for a sample using the Open Epi program, ranging in age from 25 to 65 and of either gender. Patients who tested positive for malarial parasites and had fever >104°F for longer than 4 days accompanied with chills, and rigors were selected. Patients with undiagnosed hepatomegaly and hepatic cirrhosis were excluded. Samples of blood were gathered and delivered to the pathology lab for biochemical evaluation. SPSS version 16.0 was used for data entry and analysis. For the numerical variables (such as age of the patients and disease duration), means and standard deviations were computed. The subjective variables (gender, age groups, length divisions, and hepatic dysfunction) were evaluated as percentages and frequencies. Results: A total of 270 individuals with confirmed cases of malaria were examined, having a mean age of 39.97 + 8.91 years. There were 70 (27.5%) women and 185 (72.5%) men. A total of 100 (37.3%) individuals with malaria had hepatic impairment. The only factor that significantly correlated (p0.03) to hepatic dysfunction was the length of the illness, whereas gender and various age categories did not. Conclusions: Only the length of the illness revealed a strong relationship between malaria and hepatic dysfunction in our research's findings (p 0.03).