Hypertriglyceridemia induced acute pancreatitis managed with low dose intravenous Insulin.

Abstract

Acute Pancreatitis caused by HTG is likely to be more severe with higher rate of complications compared to other etiologies [2,3] Therefore; rapid lowering of HTG is a priority as it improves outcome of AP [4]. Insulin emerges as safe and effective agent in lowering Triglyceride level within few days. The dose of insulin is widely variable among different studies, ranging from as low as 0.1-0.3 U/kg/h to higher doses of 6-10U/kg/h, which are usually needed in diabetic patients [5,6]. The duration of Insulin therapy is another variable among reported cases; it ranges between 2-4 days. In non-diabetic patients lower doses of Insulin are usually used [7]. Although we used the lowest reported dose ; however, it was safe and effective to lower hypertriglyceridemia within two days.