Exogenous surfactant in the late respiratory phase of COVID-19-Reference-Cited by-同舟云学术

Exogenous surfactant in the late respiratory phase of COVID-19

Published:2021-06-11 Issue:5 Volume:99 Page:7-13
ISSN:2542-1506
Container-title:Tuberculosis and Lung Diseases
language:
Short-container-title:Tuberk. bolezni lëgk.

Author:

Shapovalov K. G.¹,Lukyanov S. А.¹,Konnov V. А.¹,Rozenberg O. А.²

Affiliation:

1. Chita State Medical Academy

2. A. M. Granov Russian Research Center of Radiology and Surgical Technology

Abstract

The article presents data on the course of inhalations with a native surfactant administered in two patients (66 and 53 years old) at the late respiratory phase of the new coronavirus infection of COVID-19 (the 22nd and the 19th days from the disease onset) who received non-invasive artificial lung ventilation.Subjects and methods. For inhalations, an AeroNeb™ micropump nebulizer was used; for one inhalation, 75 mg of surfactant-BL was dissolved in 5 ml of isotonic sodium chloride solution. The treatment course included 5 days with 2 inhalations a day.Results. In both patients, upon the end of this therapy with the native surfactant, regression of respiratory failure was noted, the level of respiratory support was reduced to insufflation with humidified oxygen, and rehabilitation measures were started with subsequent discharge from the hospital.

Publisher

New Terra

Subject

General Medicine

Reference22 articles.

1. Аveryanov А.V., Klypa T.V., Balionis O.I., Bychinin M.V., Chernyak А.V., Troitskiy А.V. Inhaled surfactant for high-flow oxygen therapy in COVID-19 patients: results of a retrospective analysis. Remedium, 2020, no. 7-8, pp. 84-88. (In Russ.)

2. Аlekseev А.M., Yakovlev А.А., Shvechkova M.V., Seyliev А.А., Volchkov V.А., Rozenberg O.А. Surfactant therapy for pneumonia and ARDS associated with A/H1N1 virus. Zabaikalsky Med. Journal, 2011, no. 1, pp. 23-27. (In Russ.)

3. Bautin А.E. The use of the combination of the alveolar mobilization maneuver and endobronchial administration of an exogenous surfactant in comprehensive therapy of acute respiratory distress syndrome after cardiac surgery. Vestnik Intensivnoy Terapii, 2015, no. 1, pp. 3-11. (In Russ.)

4. Bautin А.E., Аvdeev S.N., Seyliev А.А., Shvechkova M.V., Merzhoeva Z.M., Trushenko N.V., Semenov А.P., Lapshin K.B., Rozenberg O.А. Inhalation surfactant therapy in the integrated treatment of severe COVID-19 pneumonia. Tuberculosis and Lung Diseases, 2020, vol. 98, no. 9, pp. 6-13. (In Russ.)

5. Vlasenko А.V., Ostapchenko D.А., Moroz V.V., Rozenberg O.А. The use of BL-surfactant in adults with acute respiratory distress syndrome of various genesis. Obschaya Reanimatologiya, 2005, no. 6, pp. 21-29. (In Russ.)

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Clinical observation of the long-term course of COVID-19 infection in a patient with an immunodeficiency condition;Meditsinskiy sovet = Medical Council;2024-04-11

2. Complex treatment of destructive pulmonary tuberculosis using inhaled tauractant therapy;Meditsinskiy sovet = Medical Council;2023-11-16

3. Role of surfactant in the pathogenesis of bronchopulmonary pathology;Meditsinskiy sovet = Medical Council;2023-10-12

4. Inhalations with surfactant-BL in the late respiratory phase of COVID-19 in the patient with a severe course of the disease;Tuberculosis and Lung Diseases;2022-06-09