Epidemiological aspects of tuberculosis in HIV infected children-Reference-Cited by-同舟云学术

Epidemiological aspects of tuberculosis in HIV infected children

Published:2020-10-26 Issue:9 Volume:98 Page:33-37
ISSN:2542-1506
Container-title:Tuberculosis and Lung Diseases
language:
Short-container-title:Tuberk. bolezni lëgk.

Author:

Vasilieva E. B.¹,Lozovskaya M. E.¹,Klochkova L. V.¹,Yarovaya Yu. A.¹,Noskova O. M.²

Affiliation:

1. St. Petersburg State Pediatric Medical University

2. Children Infectious Hospital no. 3

Abstract

The objective: to assess the methods and time of detection of tuberculosis and HIV infection in children with the co-infection, epidemiological risk factors to develop tuberculosis and effectiveness of preventive measures.Subjects and methods. 75 children in the age from 0 to 14 years old were enrolled in the study. The TB/HIV Group included 25 children with TB/HIV co-infection. The TB Group included 50 HIV negative children with tuberculosis, they made a comparison group.Results: out of 25 children with TB/HIV, only 18 (72%) were aware of perinatal exposure to HIV. HIV infection was confirmed in 11/25 (44%) children during the first months of life, in the remaining 14/25 (56%) it was confirmed later, the latest at 13 years old. In 4 children, HIV infection was detected during examination for tuberculosis. In the TB/HIV Group, in 14/25 (56%) children were exposed to tuberculosis in their families as well as 35/50 (70%) in the TB Group. The positive result of a sputum test of the index case was registered in 7/14 (50%) children of the TB/HIV Group and 19/35 (54.2%) children of the TB Group. Of 25 children of the TB/HIV Group, 17 children (68%) were vaccinated with BCG, and in 9 of them the vaccination was not done properly.

Publisher

New Terra

Subject

General Medicine

Reference8 articles.

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