High Flow Oxygen Therapy in Patients with Burn Injury-Reference-Cited by-同舟云学术

High Flow Oxygen Therapy in Patients with Burn Injury

Published:2021-07-13 Issue:3 Volume:18 Page:46-52
ISSN:2541-8653
Container-title:Messenger of ANESTHESIOLOGY AND RESUSCITATION
language:
Short-container-title:Vestn. anesteziol. reanimatol.

Author:

Ponomarev А. А.¹,Kazennov V. V.¹,Kudryavtsev А. N.¹,Korneev А. V.¹,Аlekseev А. А.¹

Affiliation:

1. A. V. Vishnevsky Institute of Surgery

Abstract

Some patients with severe burn injury have a high risk of developing acute respiratory failure, the cause of which may be interstitial pulmonary edema caused by inadequate infusion therapy.The objective: to evaluate the effectiveness of high-flow oxygen therapy (HFOT) in acute parenchymatous respiratory failure in burn patients.Subjects and methods. The prospective analysis included 74 patients with ARF in the stage of burn toxemia, without inhalation trauma, with PaO2/FiO2 below 300. In Main Group (37 patients), HFOT was used, while in Control Group patients received oxygenation through nasal cannula with the rate up to 15 l/min. Parameters of respiratory rate, PaO2/FiO2, PaCO2, MAP, heart rate, the number of intubations, respiratory comfort were recorded within 48 hours.Results. Main Group had higher values of oxygenation index in 48 hours of the trial (342 vs. 305.5, p = 0.02), faster normalization of blood gas composition compared to Control Group. HFOT was associated with greater respiratory comfort (8.4 vs. 5.3 VAS scores, p = 0.03), lower need in mechanical ventilation (4 vs. 11, p = 0.04).Conclusion: HFOT is an effective method for the treatment of respiratory failure in inpatients with burns. The need for intubation decreases, it is more comfortable to be tolerated than standard methods of oxygen therapy.

Publisher

New Terra

Subject

General Materials Science

Reference13 articles.

1. Аlekseev А.А., Bobrovnikov А.E., Bogdanov S.B. Ozhogi termicheskiye i khimicheskiye. Ozhogi solnechnyye. Ozhogi dykhatelnykh putey: Klinicheskiye rekomendatsii. [Thermal and chemical burns. Solar burns. Respiratory tract burns. Clinical guidelines]. Moscow, 2017, 115 p. pp. 12. http://combustiolog.ru/wp-content/uploads/2013/07/Natsional-ny-e-klinicheskie-rekomendatsiipo-ozhogam-20171.pdf.

2. Аlekseev А.А., Bobrovnikov А.E., Malyutina N.B. Emergency and urgent medical care after burn injury. Meditsinsky Alfavit, 2016, vol. 2, no. 15, pp. 6‒12. (In Russ.) https://elibrary.ru/download/elibrary_30478917_22467782.pdf.

3. Vlasenko А.V., Koryakin А.G., Evdokimov E.А. High-flow oxygen therapy in the treatment of acute respiratory failure of various origins: opportunities and prospects. Meditsinsky Alfavit, 2017, vol. 3, no. 29, pp. 16‒26.(In Russ.) https://www.med-alphabet.com/jour/article/view/328/328.

4. Lavrov V.А. Molecular mechanisms of inflammation in the burned. Epub. Kombustiologiya, 2003, no. 15. (In Russ.) http://combustiolog.ru/journal/molekulyarny-e-mehanizmy-vospaleniya-u-obozhzhenny-h.

5. Boyer F., Vargas M., Delacre M. Prognostic impact of high-flow nasal cannula oxygen supply in an ICU patient with pulmonary fibrosis complicated by acute respiratory failure. Intens. Care Med., 2011, vol. 37, pp. 558–559. https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00279.2016.