Development and Validation of a Deep Learning System to Detect Glaucomatous Optic Neuropathy Using Fundus Photographs

Author:

Liu Hanruo12,Li Liu3,Wormstone I. Michael4,Qiao Chunyan12,Zhang Chun5,Liu Ping6,Li Shuning12,Wang Huaizhou12,Mou Dapeng12,Pang Ruiqi12,Yang Diya12,Zangwill Linda M.7,Moghimi Sasan7,Hou Huiyuan7,Bowd Christopher7,Jiang Lai3,Chen Yihan12,Hu Man8,Xu Yongli9,Kang Hong10,Ji Xin11,Chang Robert12,Tham Clement13,Cheung Carol13,Ting Daniel Shu Wei14,Wong Tien Yin14,Wang Zulin3,Weinreb Robert N.7,Xu Mai3,Wang Ningli12

Affiliation:

1. Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China

2. Beijing Ophthalmology and Visual Science Key Lab, Beijing, China

3. School of Electronic and Information Engineering, Beihang University, Beijing, China

4. School of Biological Sciences, University of East Anglia, Norwich, United Kingdom

5. Department of Ophthalmology, Peking University Third Hospital, Beijing, China

6. Ophthalmology Hospital, First Hospital of Harbin Medical University, Harbin, Heilongjiang, China

7. Shiley Eye Institute, University of California, San Diego, La Jolla, California

8. Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, Beijing, China

9. Department of Mathematics, Beijing University of Chemical Technology, Beijing, China

10. College of Computer Science,Nankai University, Tianjin, China

11. Beijing Shanggong Medical Technology Co., Ltd, Beijing, China

12. Department of Ophthalmology, Byers Eye Institute at Stanford University, Palo Alto, California

13. Department of Ophthalmology and Visual Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Kowloon, Hong Kong, China

14. Singapore Eye Research Institute, Singapore National Eye Center, Singapore

Publisher

American Medical Association (AMA)

Subject

Ophthalmology

Reference34 articles.

1. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.;Tham;Ophthalmology,2014

2. The number of people with glaucoma worldwide in 2010 and 2020.;Quigley;Br J Ophthalmol,2006

3. Glaucomatous damage of the macula.;Hood;Prog Retin Eye Res,2013

4. Strategies for improving early detection of glaucoma: the combined structure-function index.;Tatham;Clin Ophthalmol,2014

5. The pathophysiology and treatment of glaucoma: a review.;Weinreb;JAMA,2014

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